{"id":40,"date":"2025-01-22T22:11:18","date_gmt":"2025-01-22T22:11:18","guid":{"rendered":"https:\/\/mrivas.su.domains\/gbe\/?page_id=40"},"modified":"2025-10-30T16:15:13","modified_gmt":"2025-10-30T16:15:13","slug":"curriculum-vitae-cv","status":"publish","type":"page","link":"https:\/\/mrivas.su.domains\/gbe\/curriculum-vitae-cv\/","title":{"rendered":"Curriculum Vitae\/CV"},"content":{"rendered":"\n<div class=\"wp-block-cover alignfull is-light has-contrast-color has-text-color has-link-color wp-elements-75d4c6b014d9e65e92e5fa2db3764486\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--60);padding-right:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--60);padding-left:var(--wp--preset--spacing--50);min-height:833px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-base-background-color has-background-dim-100 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container has-global-padding is-layout-constrained wp-container-core-cover-is-layout-873ee6b1 wp-block-cover-is-layout-constrained\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-7ee84d44 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:65%\">\n<div class=\"wp-block-group is-vertical is-content-justification-stretch is-layout-flex wp-container-core-group-is-layout-353c4f5a wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"341\" src=\"https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-12-1024x341.png\" alt=\"\" class=\"wp-image-67\" srcset=\"https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-12-1024x341.png 1024w, https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-12-300x100.png 300w, https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-12-768x256.png 768w, https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-12-1536x512.png 1536w, https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-12-2048x683.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"has-text-align-left\"><em>Elements of Life by Augusto Silva Gomez<\/em><\/p>\n\n\n\n<p class=\"is-style-text-subtitle is-style-text-subtitle--1\">My name is Manuel A. Rivas. I am an Assistant Professor in the <a href=\"https:\/\/dbds.stanford.edu\/\">Department of Biomedical Data Science<\/a> at <a href=\"https:\/\/stanford.edu\/\">Stanford University<\/a>.<\/p>\n\n\n\n<p>I&#8217;ve led a team of PhD students, postdocs, and staff scientists at Stanford. We focus on developing statistical and computational methods for the analysis of population-scale datasets. Our goals are to:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Generate effective therapeutic hypotheses from human genetic data;<\/li>\n\n\n\n<li>Train risk prediction models for rare and common diseases;<\/li>\n\n\n\n<li>Develop artificial intelligence tools for tumor board discussions of rare disease patients;<\/li>\n\n\n\n<li>Create optimized algorithms for population-scale datasets.<\/li>\n<\/ol>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:35%\">\n<div class=\"wp-block-group is-vertical is-content-justification-stretch is-nowrap is-layout-flex wp-container-core-group-is-layout-73b0033c wp-block-group-is-layout-flex\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"1000\" src=\"https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-10.png\" alt=\"\" class=\"wp-image-43\" srcset=\"https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-10.png 1000w, https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-10-300x300.png 300w, https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-10-150x150.png 150w, https:\/\/mrivas.su.domains\/gbe\/wp-content\/uploads\/2025\/01\/image-10-768x768.png 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n\n<p class=\"has-text-align-right has-x-large-font-size\" style=\"line-height:1.2\"><a href=\"https:\/\/scholar.google.com\/citations?user=BRAWeqYAAAAJ&amp;hl=en\">Google Scholar<\/a> (h-index 64: Citations: 70,513, i10-index: 118)<br><a href=\"https:\/\/www.linkedin.com\/in\/manuel-rivas-55b04617\">LinkedIn<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p class=\"has-text-align-left\"><strong>Academic History<\/strong><\/p>\n\n\n\n<p><strong>2016 to Present <\/strong>Assistant Professor, University Tenure Line, Department of Biomedical Data Science, Stanford University, Stanford, USA<\/p>\n\n\n\n<p><strong>2010 to 2015<\/strong> DPhil, Nuffield Department of Clinical Medicine, Human Genetics, University of Oxford, Oxford, UK<\/p>\n\n\n\n<p class=\"has-text-align-left\"> <strong>2004 to 2008<\/strong> B.S. Mathematics, Massachusetts Institute of Technology, Cambridge, MA, USA<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>Scholarships and Honors<\/strong><\/p>\n\n\n\n<p><strong>2025 <\/strong>MIT <a href=\"https:\/\/mites.mit.edu\/discover-mites\/mites-summer\/\">MITES<\/a> Innovator Award. Background <a href=\"https:\/\/www.broadinstitute.org\/news\/data-scientist-and-former-student-researcher-shares-how-broad-institute-helped-guide-his-career\">profile<\/a>. <\/p>\n\n\n\n<p><strong>2017<\/strong> Regional Prize B3 Panama<\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>2016 <\/strong>NDM Graduate Prize Winner, University of Oxford<\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>2010<\/strong> NDM Osler Award Winner, University of Oxford<\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>2010 <\/strong>Clarendon Scholarship, University of Oxford<\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>2004 to 2008 <\/strong>Gates Millenium scholarship, Bill and Melinda Gates Foundation<\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>2004 <\/strong>Exxon Mobil State and National Scholar, Exxon Mobil<\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>2004 <\/strong>Ford Foundation Scholastic Award<\/p>\n\n\n\n<p class=\"has-text-align-left\"><strong>2004 <\/strong>Advanced Placement National Scholar  <\/p>\n\n\n\n<p class=\"has-text-align-left\"><\/p>\n\n\n\n<p><strong>Secured Funding<\/strong><\/p>\n\n\n\n<p><strong>2024 to 2027 <\/strong>Award from the Advanced Research Projects Agency for Health&nbsp;(<a href=\"https:\/\/arpa-h.gov\/\">ARPA-H<\/a>). <em>Artificial Intelligence for Tumor Board Program<\/em>. <strong>Principal Investigator<\/strong>.<\/p>\n\n\n\n<p><strong>2021 to 2026 <\/strong>NIH R01 Award from National Institutes of Mental Health. <a href=\"https:\/\/reporter.nih.gov\/search\/IFfmCud3YEqVItMKqvULCg\/project-details\/10768753\"><em>Identifying causal genetic variants and molecular mechanisms impacting mental health<\/em><\/a>. <strong>Principal Investigator<\/strong>.<\/p>\n\n\n\n<p><strong>2016 to 2020<\/strong> NIH R01 Award from National Human Genome Research Institute. <em>Software for Large-scale inference of biomarkers, rare, and common diseases.<\/em> <strong>Principal Investigator<\/strong>.<\/p>\n\n\n\n<p><strong>2020<\/strong> Takeda Inc. <em>Mapping the genetics of COVID-19. <\/em><strong>Principal Investigator<\/strong>.<\/p>\n\n\n\n<p><strong>2018<\/strong> Sanofi US. <em>Machine learning models for dissecting the genetics of Asthma<\/em>. <strong>Principal Investigator<\/strong>.<\/p>\n\n\n\n<p><strong>2016 to 2020<\/strong> NHGRI Genome Sequencing Coordinating Center. Sucontract PI. <\/p>\n\n\n\n<p><strong>2019 to 2021 <\/strong>NIH R01 Distinguishling clinical and genetic risk of suicide ideation. Subcontract PI. <\/p>\n\n\n\n<p><strong>2019 to 2022 <\/strong>NIH NHGRI Center for Multi-ethnic mapping of Mendelian and Complex Diseases. Subcontract PI. <\/p>\n\n\n\n<p><strong>Patents<\/strong><\/p>\n\n\n\n<p><strong>2024 <\/strong>US Patent #12,100,480 Granted. <em><a href=\"https:\/\/patentimages.storage.googleapis.com\/4e\/d3\/83\/67e4c92ca4682d\/US12100480.pdf\">Assessment of polygenic trait risk via trait components and applications thereof<\/a><\/em>. <strong>Inventor<\/strong>. <\/p>\n\n\n\n<p><strong>2023 <\/strong>World Patent Application #WO2023212294A1. <em><a href=\"https:\/\/patentimages.storage.googleapis.com\/39\/bd\/e0\/0faffd97915f84\/WO2023212294A1.pdf\">Angiopoietin-related protein 7-specific antibodies and uses thereof<\/a><\/em>. <strong>Co-Founder of Broadwing Bio<\/strong>.<\/p>\n\n\n\n<p><strong>2023 <\/strong>World Patent Application #WO2024227154A1. <a href=\"https:\/\/patentimages.storage.googleapis.com\/2c\/de\/6c\/f2a9009b12338a\/WO2024227154A1.pdf\">Complement component 3 (c3)-specific antibodies and uses thereof<\/a>. <strong>Co-Founder of Broadwing Bio<\/strong>.<\/p>\n\n\n\n<p><strong>2021 <\/strong>US Patent Application #17\/079,11. <a href=\"https:\/\/patentimages.storage.googleapis.com\/b0\/3f\/a1\/de454e769eb047\/US20210123932A1.pdf\"><em>Genetic determination of hormone levels and applications thereof<\/em>.<\/a> <strong>Inventor<\/strong>.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Companies Founded<\/strong><\/p>\n\n\n\n<p><strong>2020 to Present<\/strong> <a href=\"https:\/\/broadwing.bio\/\">Broadwing Bio<\/a>. <em>Envisioning an end to blindness.<\/em> Antibody therapeutics company to treat major causes of adult vision loss guided by genetically validated targets.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Scientific Advisory Boards<\/strong><\/p>\n\n\n\n<p><strong>2024 to present<\/strong> <a href=\"https:\/\/www.biopharmadive.com\/news\/braveheart-hengrui-hypertrophic-cardiomyopathy-china-licensing-deal\/759365\/\">Braveheart Bio<\/a>. <em>Founding advisor<\/em>. Heart disease biotechnology company focused on hypertrophic cardiomyopathy.<\/p>\n\n\n\n<p><strong>2018 to 2022<\/strong> <a href=\"https:\/\/mazetx.com\/\">Maze Therapeutics<\/a>. <em>Maze Fellow<\/em>. Kidney disease biotechnology company focused on genetically validated targets. <\/p>\n\n\n\n<p><strong>2019 <\/strong><a href=\"https:\/\/www.related.vc\/\">Related Sciences<\/a>. Data science driven drug foundry.<\/p>\n\n\n\n<p><strong>2018 <\/strong><a href=\"https:\/\/paradigm4.com\/\">Paradigm4<\/a>. Data sciences analytics company.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Employment<\/strong><\/p>\n\n\n\n<p><em>Stanford allows annual leave to its faculty. I took two years of leave during COVID to learn about company formation and building biotechnology companies.<\/em><\/p>\n\n\n\n<p><strong>2022 to 2023 <\/strong>Head of Statistical Genetics. Maze Therapeutics.<\/p>\n\n\n\n<p><strong>2021 to 2022 <\/strong>VP of Human Genetics. <a href=\"https:\/\/investors.biogen.com\/news-releases\/news-release-details\/biogen-completes-acquisition-human-immunology-biosciences\">HIBio<\/a>.<\/p>\n\n\n\n<p><strong>2014 to 2016<\/strong> Computational Scientist. <a href=\"https:\/\/broadinstitute.org\/\">Broad Institute<\/a>.<\/p>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-40","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/mrivas.su.domains\/gbe\/wp-json\/wp\/v2\/pages\/40","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mrivas.su.domains\/gbe\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mrivas.su.domains\/gbe\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mrivas.su.domains\/gbe\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mrivas.su.domains\/gbe\/wp-json\/wp\/v2\/comments?post=40"}],"version-history":[{"count":23,"href":"https:\/\/mrivas.su.domains\/gbe\/wp-json\/wp\/v2\/pages\/40\/revisions"}],"predecessor-version":[{"id":563,"href":"https:\/\/mrivas.su.domains\/gbe\/wp-json\/wp\/v2\/pages\/40\/revisions\/563"}],"wp:attachment":[{"href":"https:\/\/mrivas.su.domains\/gbe\/wp-json\/wp\/v2\/media?parent=40"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}